회원학회

회원학회

번호 연구제목 연구자 연구기간 발표실적
내용
97 麻黃 Hexane 분획물이 생쥐의 지질 대사에 미치는 영향 김경민, 김영균, 신길조 2014-01-01 ~ 학회지
- Objectives : This study was designed to investigate the effects of Ephedra Herba hexane fraction on lipid levels in serum and lipid accumulation in liver tissue in Hyperlipidemic mice.
- Methods : Hyperlipidemia was induced by providing high fat diet for 4 weeks. Normal group was provided with normal diet. CTL groupwas provided with high fat diet. Ephedra Herba hexane fraction group was provieded with high fat diet and administered orally in the concentration of 1.5mg/kg body weight/day for 2 weeks. In this experiment, effects on total cholesterol, HDL-cholesterol, triglyceride, AST, ALT, fasting blood glucose in serum were measured. In addition histopathological changes in liver tissue were also observed.
- Results : Ephedra Herba hexane fraction did not affects weight gain, serum AST and ALT in hyperlipidemic mice. Oral administration of Ephedra Herba hexane fraction lowered levels of total cholesterol and triglyceride, which were elevated by induction of hyperlipidemia. In addition, Ephedra Herba hexane fraction group showed downward tendency of lipid accumulation
compared with CTL group. Finally, administration of Ephedra Herba hexane fraction lowered fasting blood glucose significantly. And Ephedra Herba hexane fraction also ameliorates anti-oxidative stress systems in internal organs which play key role in disease prevention.
- Conclusion : These results suggest that Ephedra Herba hexane fraction can prevent lipid accumulation in liver tissue through regulation of dyslipidemia and hyperglycaemia.
96 五味子 헥산 분획 추출물이 고지방 식이에 의한 고지혈증 생쥐의 지질대사 및 간 조직 유전자 발현에 미치는 영향 김현영, 박선미, 김영균 2014-01-01 ~ 학회지
- Objectives : The berries of Schisandra chinensis (Schisandra Fructus) are given the name Omiza in Koreane(五味子), and have been used asremedies for many ailments: to resist infections, increase skin health, and combat insomnia, coughing, and thirst. This study was designed to investigate the effects of Schisandra Fructus hexane fraction (SFH) on serum lipid levels in Hyperlipidemic mice.
- Methods : In this experiment, effects on total cholesterol, HDL-cholesterol, triglyceride, AST, ALT, fasting blood glucose in serum were measured. And in addition, histopathological and gene expression changes in liver tissue was also observed.
- Results : SFH did not affects weight gain, serum AST and ALT in hyperlipidemic mice. Oral administration of SFH lowered levels of total cholesterol and triglyceride, which were elevated by induction of hyperlipidemia. Finally, administration of SFH lowered fasting blood glucose
significantly. And SFH also ameliorates anti-oxidative stress systems in internal organs which
play key role in disease prevention.
- Conclusion : Results in our study suggest that SFH can prevent obese through regulation of dyslipidemia and hyperglycaemia
95 뇌경색 환자의 경동맥 초음파 검사와 한방 중풍 변증과의 관련성 연구 김경민 2014-01-01 ~ 학회지
- Objectives : The purpose of this study was to investigate the correlation of The Korean Standard Pattern Identification for Stroke and Intima-Media Thickness of common carotid artery(CCA-IMT).
- Methods : 100 subjects with acute ischemic stroke were recruited from the patients admitted to Dong-Eui Medical Center from the June 2011 to January 2014. We assessed 100 patient’s Common Carotid Intima Media Thickness data by B Mode ultrasonography. We investigated pattern identification of all subjects based on Korean Standard Pattern Identification for Stroke-Ⅲ. then, We analyzed their characteristics, risk factor, blood test result, life style.
- Results : We analyzed indicators of Korean Standard Pattern Identification for Stroke-Ⅲ by Common Carotid Intima Media Thickness difference. As a result, pale complexion, look powerless, drowsiness like to lie, heat vexation and aversion to heat were significantly higher in the CCA-IMT ? 1.0mm group then in the CCA-IMT 〈 1.0mm group.
- Conclusion : According to the analysis, the Relationship between Carotid Intima-Media Thickness and The Korean Standard Pattern Identification for Stroke in Ischemic Stroke Patients were founded. To acquire more concrete conclusion on this theme, we need more research.
94 감각장애를 동반한 Thalamic Ataxia 환자 치험 1례 이보윤, 이현중, 이동혁, 두경희, 김수경, 조승연, 박정미, 고창남, 배형섭, 박성욱 2014-01-01 ~ 학회지
This report is about a case of an ataxia patient with sensory loss diagnosed with thalamic Infarction. The patient had symtoms of gait disturbances and dysmetria. We used Korean medicine treatment modalities including acupunture, electroacupuncture, moxibustion and herb medicines. The improvement of ataxia was evaluated by International Cooperative Ataxia Rating Scale and Balance master? system. After treatment, decreased scores of International Cooperative Ataxia Rating Scale and change of the trace of Balance master? system showed that symtoms of ataxia were improved. Sensory deficits and other conditions were also getting better. This report suggests that Korean medicine could have a therapeutic effect for Thalamic ataxia.