회원학회

회원학회

번호 연구제목 연구자 연구기간 발표실적
내용
29 <황제내경 소문 상고천진론>의 양생법과 공동체 기반 건강 노화 요인의 비교고찰 최정은, 류호룡, 박미소 2024.03.23 ~ 학회지
We reexamined the meaning of by drawing on findings from studies on Blue Zones and healthy communities. The first chapter of Sanggocheonjinron highlighted the concept of living in harmony with the principles and essence of the universe. It emphasized the importance of a balanced diet, coupled with a regular lifestyle, as fundamental factors for achieving health and longevity. Chapter 2 highlighted the significance of harmonious community living as a key element for overall well-being. Chapter 4 further emphasized the importance of living one’s life in accordance with the principles of nature and community living. Numerous investigations into longevity and well-being have been conducted. Notably, an examination of the lifestyle of elderly people living in Blue Zones—regions densely populated with people living beyond 100 years without significant health issues—demonstrated that these people thrive by embracing a sense of purpose, leading simple lives, engaging in natural daily activities, and effectively managing stress. According to the findings, eating a vegetarian diet, avoiding excessive eating and drinking, and cultivating connections within a healthy community and family all helped to maintain health. While genetic factors were acknowledged to contribute to human longevity, constituting approximately 25%, the remaining portion was recognized as being influenced by lifestyle choices. Consequently, the pursuit of a healthy and long life, as advocated in the Hwangjenaegyeong and Blue Zones, emphasized the importance of belonging to a healthy community and cultivating healthy lifestyle habits.
28 비만 치료에서 마황 및 에페드린의 안전성 고찰: 간을 중심으로 김은주, 이윤진, 임영우 2024.03.19 ~ 학회지
Objectives The purpose of this study is to examine whether the use of Ephedrae herba and Ephedrine in obesity treatment is safe for the liver.
Methods Toxicology studies and randomized controlled trials (RCTs) from systematic review (SR), meta-analysis related to Ephedrae herba or Ephedrine, which refer to liver function were collected through Pubmed and RISS databases. Results There were no findings that hepatotoxicity was induced by Ephedrae herba in the 2-week acute, 4-week sub- acute, and 13-week repeated administration toxicology studies. In the RCT studies of Ephedrae herba, Ephedrine, or herbal medicine including Ephedrae herba, there were no significant changes in liver function levels.
Conclusions This study suggests that it is difficult to find clear evidence that Ephedrae herba and Ephedrine cause liver injury.
27 과체중 또는 비만인 소아청소년의 체중 감량을 위한 가미태음조위탕의 임상활용: 다기관, 후향적 차트 리뷰 박규경, 유영재, 방지현, 박민정, 고덕재, 노은영 2024.02.07 ~ 학회지
Objectives The purpose of this study is to evaluate the effects of Gamitaeeumjowi-tang on the weight changes and adverse events in overweight or obese prediatric-adolescents.
Methods A multicenter and retrospective chart review was performed on 425 overweight and obese pediatric-adolescents who took Gamitaeeumjowi-tang from May 2022 to November 2023. Outcomes were measured in terms of total weight loss and weight loss percentage, as well as the percentage of patients who lost at least 5% and 10% of their baseline weight. Patient-reported adverse events were collected and analyzed for frequency of occurrence, and whether they were serious enough to require discontinuation.
Results A total of 47 patients were included, with a mean (±standard deviation) age of 15.00±1.90 years, weight of 85.59 ±19.24 kg, and body mass index of 30.81±4.98 kg/m ; 74.47% were female. The mean (±standard deviation) weight loss
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was 8.84±4.93 kg and the mean weight loss rate was 10.23±4.28%. The percentage of patients who lost at least 5% and 10% of their baseline weight was 95.74% and 54.20% respectively. No serious adverse events were reported. Conclusions Gamitaeeumjowi-tang was shown to help pediatric-adolescents who were overweight or obese to lose weight, and no serious adverse events were associated with discontinuation of the medication. Further well-designed clinical studies are recommended.
26 정상 체중 비만 성인의 체지방 감량을 위한 한약 처방의 활용: 후향적 차트 리뷰 김수현, 석정미, 옥지명 2024.02.05 ~ 학회지
Objectives Normal weight obesity (NWO) is defined as a normal body weight according to Body Mass Index (BMI) but with a high body fat percentage. NWO is associated with metabolic abnormalities and cardiovascular risk factors, thereby emphasizing the importance of body fat loss. The objective of this study is to evaluate changes in weight and body fat with NWO who were prescribed Korean herbal medicine.
Methods A retrospective chart review was conducted for subjects with NWO, within the normal weight range but with over 30% body fat percentage. These subjects were prescribed herbal medicine for a 12-week between March 2021 and May 2023. Weight (kg), body fat mass (kg), body fat percentage (%) and % Fat Free Mass (FFM) loss/weight loss (%FFML) were assessed before and after the period. Reported adverse events were evaluated for severity, causality, and system-organ classes. Results A total of 42 subjects were included (mean±SD, weight 57.38±3.45 kg, body fat percentage 33.65±2.12%). The average weight loss rate was 6.99±3.22% with a reduction of 4.08±1.95 kg, while the body fat loss rate averaged 18.00± 0.08% with a decrease of 3.54±1.73 kg. The average of %FFML was 21.89±0.16%. Most adverse events reported were mild (90.9%) in severity, and the likelihood of events being 'Unlikely' increased from 48.8% to 64.3% as the program progressed. Conclusions The administration of Korean herbal medicine can be considered an appropriate method to alleviate normal weight obesity, without causing serious adverse reactions. Further well-designed controlled trials and clinical studies with the analysis of hematological indicators are needed to validate its efficacy.
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