회원학회
회원학회
| 번호 | 연구제목 | 연구자 | 연구기간 | 발표실적 |
|---|---|---|---|---|
| 내용 | ||||
| 106 | 파킨슨병 동물 모델을 이용한 신정격 사암침법의 도파민성 신경세포 보호 효과 연구 | 김승태, 이상협, 김보경 | 2022-01 ~ | 학회지 |
| Objectives : Saam acupuncture is one of the indigenous therapeutic modalities in traditional Korean medicine. In this study, the neuroprotective effect of Saam acupuncture of kidney tonification was investigated using 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-treated mice. Methods : Twelve-week-old male C57BL/6 mice were intraperitoneally administered with 30 mg/kg of MPTP at 24-h intervals for 5 days and acupuncture stimulation at LU8, KI7, SP3 and KI3 was performed once a day for 12 days from the first MPTP injection. The pole test and the rotarod test were performed to evaluate motor function, and dopaminergic neuronal survival in the substantia nigra (SN) and striatum was evaluated using tyrosine-hydroxylase immuno - histochemistry. Results : MPTP administration caused behavioral impairment and dopaminergic neuronal death in the nigro- striatal pathway. Whereas the Saam acupuncture treatment alleviated the MPTP-induced motor dysfunction and dopaminergic neuronal death in the SN and striatum. Conclusions : Saam acupuncture of kidney tonification can alleviate the MPTP-induced motor dysfunction and dopaminergic neuronal death in the nigrostriatal pathway, uggesting a possible role for acupuncture in the treatment of Parkinson’s disease. Key words : Saam acupuncture, acupoint, kidney meridian deficiency, Parkinson’s disease, 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) |
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| 105 | 침구치료로 개선된 장애인의 정신건강 증례보고 | 고원준, 박상균 | 2022-01 ~ | 학회지 |
| The purpose of this study is to report the case mental health of people with disabilities has improved through visit treatment atpublic health centers. From October 26, 2021 to January 04, 2022, 6 visits were conducted and Patient Health Questionnaire-9 (PHQ-9), Beck Depression Inventory (BDI), Korean version of Center for Epidemiological Studies-Depression Scale (K-CES-D), Visual Analog Scale (VAS), Euro Qol-Visual Analogue Scale (EQ-VAS), Modified Barthel Index (MBI) were used to check changes. After Korean Medicine treatments such as acupuncture, electroacupuncture, electromoxibustion, PHQ-9 decreased from 18 to 8, BDI decreased from 22 to 15, K-CES-D decreased from 42 to 21. And VAS decreased from 85 to 50, EQ-VAS increased from 30 to 50. But There was no change in the MBI. Confirmation of improvement in mental health-related indicators of disabled patients through Korean Medicine treatments. Key words : disabled, acupuncture, mental health, electroacupuncture, electromoxibustion, case reports |
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| 104 | 관합추 배속에 따른 삼음삼양의 경락학적 분포 | 김병호, 백유상, 임사비나 | 2022-01 ~ | 학회지 |
| Objectives : The purpose of this study is to establish a Korean medical perspective on the human body through understanding of the meridians according to the distribution of the three yin and three yang (삼음삼양) and the opening, closing and pivot (관합추) as defined in ≪Huangdi’s Internal Classic≫. Methods : A total of 8 medical databases including KISS, Earticle, DBpia, RISS, OASIS, KMbase, and ScienceON were used to search studies published through July 2021, and literature was included without limitations on the publication period. The search terms were “(meridian OR acupoint OR meridian sinew) AND position” OR “Gwan-Hap-Chu” OR “Gae-Hap-Chu” OR “three yin and three yang”. Two researchers independently made choices among the searched literature based on the preplanned selection/exclusion criteria. The search terms were“(meridian OR acupoint OR meridian sinew) AND position” OR “Gwan-Hap-Chu” OR “Gae-Hap-Chu” OR “three yin and three yang”. Results : Of the 36 obtained from the survey, 19 (53%) followed the definitions of “internal diameter” for “three yin and three yang” and “the opening, closing and pivot,” but 6 (about 16%) took a neutral position and 10 (22%) avoided mentioning. Therefore, it was judged that research was needed to end the debate on the distribution of ‘three yin and three yang’ and ‘the opening, closing and pivot’. In order to apply the definition of ≪Huangdi’s Internal Classic≫ on ‘distribution of the three-yin and three-yang’ and ‘the opening, closing and pivot’ to the upper limb and lower limb as well as the torso of the human body, this author proposed a human body model with both upper limb and lower limb attached, inspired by the posture of the fetus in the developmental stage. Conclusions : In this study, using a new human body model, it was revealed that the distribution of the three yin and three yang and the opening, closing and pivot’ as defined in the ≪Huangdi’s Internal Classic≫ can be applied not only to the torso of the human body, but also to the upper limb and lower limb. Based on the understanding of meridians, the selection of meridians in the clinical acupuncture should be made accurately, and continuous interest and research on this are expected. Key words : three yin and three yang, opening, closing and pivot, Gwan-Hap-Chu, Gae-Hap-Chu, meridianological distribution, Huangdi’s Internal Classic |
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| 103 | 한방건강보험약 12종의 항산화 활성 및 신경세포 독성 스크리닝 연구 | 서지은, 이한울, 배창환, 윤동학, 김희영, 김승태 | 2022-01 ~ | 학회지 |
| Objectives : Parkinson’s disease (PD) is a neurodegenerative disease caused by dopaminergic neuronal death in the substantia nigra pars compacta. PD is known to be linked with mitochondrial dysfunction and increased oxidative stress. In this study, anti-cytotoxic and anti-oxidative effect of 12 herbal formulae were compared. Methods : According to experts’ advice, 12 types of herbal formulae (Gamisoyosan, Galgeuntang, Galgeunhaegitang, Banhabaekchoolcheonmatang, Bojungikgitang, Boheotang, Sihogyejitang, Sihosogantang, Sihocheonggantang, Ojeoksan, Cheongsanggyeontongtang and Palmultang) were selected from 56 types of herbal formulae covered by the National Health Insurance Service in Korea. To detect anti-oxidative effect, 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay was performed, and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was performed to detect anti-cytotoxic effect of 12 herbal formulae using SH-SY5Y human neuroblastoma cells. Results : In DPPH assay, anti-oxidant activity was increased in a dose-dependent manner and half maximal inhibitory concentration was highest in the order of Galgeuntang, Gamisoyosan, Galgeunhaegitang, Ojeoksan, Palmultang, Sihogyejitang, Sihosogantang, Cheongsanggyeontongtang, Sihocheonggantang, Bojungikgitang, Boheotang and Banhabaekchoolcheonmatang. In MTT assay, concentration of 80% cell survival was highest in the order of Sihosogantang, Cheongsanggyeontongtang, Sihocheonggantang, Sihogyejitang, Bojungikgitang, Galgeuntang, Ojeoksan, Boheotang, Palmultang, Galgeunhaegitang, Banhabaekchoolcheonmatang and Gamisoyosan. Formulae with more than 50% DPPH radical scavenging activity at concentrations for 80% cell survival were Sihosogantang, Cheongsanggyeontongtang, Sihogyejitang, Galgeuntang and Sihocheonggantang. Conclusions : Sihosogantang, Cheongsanggyeontongtang, Sihogyejitang, Galgeuntang and Sihocheonggantang extracts can be candidate medicines for PD, but the effect should be validated in PD models. Key words : Parkinson’s disease, national health insurance, Korean medicine, antioxidant, herb, formula |
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