회원학회
회원학회
| 번호 | 연구제목 | 연구자 | 연구기간 | 발표실적 |
|---|---|---|---|---|
| 내용 | ||||
| 94 | 7종 문헌을 통한 오수혈 자침 깊이에 대한 고찰 | 오준엽, 김안나, 이종란, 오용택 | 2022-01 ~ | 학회지 |
| Objectives : The purpose of this study was to investigate the needling depth of five-phase acupoints by acupuncture and moxibustion literatures. Methods : 7 volumes of acupuncture and moxibustion literatures was used to determine the depth of five-phase acupoints. The depth of needling at 60 five-phase acupoints was compared between well, spring, stream, river, sea acupoints and also yin, yang, hand and foot meridians. Results : The proximal part of the extremities had deeper needling depth than the distal part of the extremities. The order of well, spring, stream, river, sea can be related to the needling depth. Foot meridians had deeper needling depth than hand meridians. Yin meridians had deeper needling depth at Well, spring, stream acupoints and yan meridians had deeper needling depth at river, sea acupoints. Conclusions : The distinct patterns of needling depth of five-phase acupoints is related to which part of the extremities are five-phase acupoints located. Key words : acupuncture, needling depth range, five-phase acupoints |
||||
| 93 | 국내 학술지에 발표된 족삼리 전침 연구 동향 분석 | 박성현, 송용하, 이승훈, 윤동학, 김승태 | 2022-01 ~ | 학회지 |
| Objectives : Electroacupuncture (EA) is a procedure in which pulses of weak electrical current are sent through acupuncture needles into acupuncture points in the skin, and Joksamli (ST36) is one of the most used acupoints. This study was designed to analyze the trend of research articles on ST36 EA published in Korea. Methods : Articles on EA at ST36 in Korean journals were searched in Korean databases and analyzed focusing on the number of publications by year, research subject, research topics, institutes, and journals. Results : Total 66 articles were included in this study, which were 51 basic researches, 12 clinical researches, and 3 reviews. Since 2000, the number of articles has gradually increased, reaching the highest level in 2007, and rapidly decreased since 2012. Kyung Hee University is the organization that published the most articles, and the journal that published the most articles is Journal of Acupuncture Research, followed by Korean Journal of Acupuncture. Conclusions : A lot of ST36 EA studies in Korean journals are basic experimental researches using rats, and the research topics are closely related to the diseases of patients visiting Korean medicine clinics. The number of papers by institution is related to the number of professors, and researchers tend to prefer publishing in acupuncture journals. Key words : acupuncture, electroacupuncture, ST36, acupoint, trend, Korea |
||||
| 92 | 족삼리 양릉천 전침 자극 후 흰쥐 통증 모델에서 microRNA의 차등 발현 | 김소희, 비슈누몰라칼라 신드후리, 구성태 | 2022-01 ~ | 학회지 |
| Objectives : Some acupoints are commonly utilized to treat a variety of diseases. The acupoints appear to have a wide range of effects caused by several mechanisms. The purpose of this study is to investigate into the potential role of microRNAs (miRNAs) in the multipotent effects of individual acupoint stimulation. Methods : We examined the miRNA expressions in the dorsal root ganglia (DRG) of neuropathic or inflammatory pain rats following ST36 and GB34 electroacupuncture (EA) stimulation. Neuropathic pain was induced by L5 spinal nerve ligation. Inflammatory pain was induced by knee joint injection of Complete Freund’s adjuvant (CFA). EA was given under gaseous anesthesia with the same parameters (1mA, 2Hz, 30 min) in 5 consecutive days. Pain behaviors and miRNA expressions were analyzed. Results : In rats with neuropathic and inflammatory pain, EA treatments significantly enhanced the paw withdrawal threshold and weight-bearing force. After nerve injury, 36 miRNAs were upregulated in the DRG of neuropathic rats, while EA downregulated 10 of them. Furthermore, 14 miRNAs were downregulated following nerve damage, while one was increased by EA. 15 miRNAs were increased in the DRG of inflammatory rats following CFA injection, while 5 were downregulated by EA. Furthermore, 17 miRNAs were downregulated following CFA injection, while 7 were increased by EA. The miRNAs rno-miR-335, rno-miR-381-5p, rno-miR-1306-3p, and rno-miR-1839-3p were regulated by EA in both models. Conclusions : In two pain models, EA applied to ST36 and GB34 regulated miRNA expression differently. There appeared to be both acupoint-specific and non-specific miRNAs, and miRNA regulation of differential protein expression may modulate a variety of EA mechanisms. Key words : acupuncture, analgesic effect, neuropathic pain, inflammatory pain |
||||
| 91 | 천마의 흑질 내 도파민성 신경세포 보호 효과에 대한 단백체학적 분석 | 배창환, 김희영, 이한울, 서지은, 윤동학, 김승태 | 2022-01 ~ | 학회지 |
| Objectives : Parkinson’s disease (PD) is a neurodegenerative disorder threatening the quality of life and highly occurred in over 65 years old. Gastrodia elata Blume (GEB), a traditional medicine used for the treatment of headache and convulsion, has been reported to have neuroprotective effect. This study was designed to investigate the neuroprotective effect of GEB and the proteomic changes in the substantia nigra (SN) of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice. Methods : Male eleven-week-old C57BL/6 mice were intraperitoneally injected with 30 mg/kg of MPTP at 24-h intervals for 5 days. Two hours after the daily MPTP injection, the mice were orally administered 800 mg/kg of GEB extract, which continued for 7 days beyond the MPTP injections, for a total of 12 consecutive days. Two hours after the final GEB administration, the brain samples were collected, and dopaminergic neuronal death and proteomic changes in the SN were evaluated. Results : GEB prevented the MPTP-induced dopaminergic neuronal death and regulated the expression of 11 proteins including thimet oligopeptidase, T-complex protein 1, glycine tRNA ligase, and pyruvate kinase isozymes M1. Conclusions : GEB prevents MPTP-induced dopaminergic neuronal death by regulating the proteins in the SN. Key words : Parkinson’s disease, Gastrodia elata Blume, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, two-dimensional electrophoresis, substantia nigra |
||||
