회원학회

회원학회

번호 연구제목 연구자 연구기간 발표실적
내용
37 대장암 수술 후 발생한 마비성 장폐색이 한의치료로 호전된 증례보고 1례 허은진, 장형민, 박수정, 김명호 2025-01 ~ 학회지
Objective: To report a case of paralytic ileus following colorectal cancer surgery that was successfully managed with Korean medicine treatment, including herbal medication, acupuncture, and moxibustion.
Methods: An 83-year-old female patient diagnosed with colorectal cancer underwent laparoscopic anterior resection and appendectomy. After surgery, she presented with abdominal distension, absence of defecation, and poor oral intake. During hospitalization at Woosuk University Korean Medicine Hospital, she received herbal medicine (Gwakhyanggunggisan), acupuncture, and moxibustion. Treatment progress was evaluated using serial abdominal X-rays and laboratory parameters.
Results: After 7 days of treatment, abdominal X-rays demonstrated a return of normal bowel gas
pattern. Laboratory findings remained unchanged, and no adverse events were observed.
Conclusion: This case suggests that integrative Korean medicine treatment, including Gwakhyanggunggisan, may be a safe and effective option for managing postoperative paralytic ileus. Further controlled studies are needed to validate these findings.
36 아로마타제 억제제 관련 근골격 증후군에서 부착형 경피신경전기자극 기기의 예비 무작위배정 대조 임상시험 프로토콜 박정향, 박은수, 김준열, 김수담, 조영민, 최미정, 유화승 2025-01 ~ 학회지
Objective: To evaluate the feasibility and safety of a wearable transcutaneous electrical nerve
stimulation (TENS) device applied to the wrist–hand region in patients with aromatase inhibitor
–associated musculoskeletal symptoms (AIMSS), and to outline exploratory clinical outcome
measures to inform a subsequent confirmatory trial.
Methods: Single-center, randomized, double-blind, sham-controlled pilot trial. Twenty women (≥40
years) with hormone receptor–positive breast cancer on aromatase inhibitors and clinically
relevant upper-limb pain (VAS ≥3) will be randomized 1:1 to active TENS or sham with
concealed allocation (variable blocks; stratified by baseline VAS, AI duration, lymphedema).
Active TENS: continuous 80–100 Hz, 80–150 μs, 20 minutes/session, twice weekly for 4
weeks, below motor threshold. Sham: identical appearance with brief initial sensation and
automated current fade-out. Feasibility/safety endpoints include recruitment, retention, adherence
(≥6/8 sessions), AE/SAE, and Bang’s blinding index. Exploratory outcomes: VAS pain (baseline,
week 2, week 4), wrist–hand ROM (Dia-Grip), Korean SF-36 v2 (acute), and opioid use
(MED). Feasibility endpoints are summarized descriptively; exploratory outcomes use linear
mixed models.
Outcomes: Primary outcomes are feasibility and safety (recruitment/retention/adherence rates,
AE/SAE profile, and blinding index). Secondary outcomes will provide preliminary estimates of
effect sizes for pain, function, quality of life, and analgesic use to guide sample size and dosing
parameters in a definitive trial.
Conclusion: This protocol tests the practicality and safety of a wrist–hand wearable TENS for
AIMSS and generates parameter and variance estimates to optimize intervention
frequency/intensity and endpoint selection in a future multicenter confirmatory RCT.
35 카페시타빈 복용 후 부작용으로 HFS를 호소하는 전이성 유방암 환자의 침 치료 후 호전 증례보고 1례 김민하, 박미선, 진예진, 최효재, 김지환, 박소정 2025-01 ~ 학회지
Objectives: Hand-foot syndrome(HFS) is a dose-limiting adverse effect of capecitabine that impairs patients’ quality of life. This case report demonstrates the efficacy of perilesional acupuncture based integrative Korean medicine treatment for capecitabine-induced Grade 3 HFS.
Methods: A 63-year-old female with metastatic breast cancer developed HFS after capecitabine treatment and was
hospitalized
for
one
m
onth
(7/
15 to 8/15).
She re
ceived
a "3-Track
acupuncture protoco
l" combining
Ba
ck-S
hu
poin
t
acupuncture,
systemic
acup
uncture, and
perilesional acupuncture, along with herbal medicine. Outcomes were evaluated using Numerical rating scale(NRS), National cancer institute-Common terminology criteria for adverse events(NCI-CTCAE) HFS grading, ADL and clinical photography.
Results: Pain decreased from NRS 6 to 0 by week 2. HFS grade improved from Grade 3 to Grade 1 with near-complete skin lesion resolution. ADL improved from walker dependency to independent ambulation. No adverse events occurred.
Conclusions: Integrative Korean medicine treatment including perilesional acupuncture significantly improved capecitabine-induced HFS through synergistic effects of autonomic regulation, pain modulation, and local blood flow improvement.
34 The Prognostic Utility of Natural Killer Cell Activity in terms of Gastric Cancer Surviva 배혜리, 박찬란, 조나현, 조정효, 손창규, 조종관, 이동수, 이남헌 2024-01 ~ 학회지
목적: 본 연구는 NK세포활성도 (NKA, Natural Killer Cell Activity)와 위암 환자의 생존율 사이의 상관 관 계를 분석하여, NKA의 위암 예후 인자로서의 활용 가능성을 평가하는 것이다.
방법: 본 연구는 대전대학교 한방병원에서 2016년 3월 1일부터 2021년 4월 24일까지 치료 받은 57명의 위암 환자의 의료 기록을 후향적으로 검토하였다. NKA 수치는 자극된 NK세포에서 방출된 interferon- γ를 통해 NKA 수치를 측정하는 혈액 검사 키트 (NK Vue®; NKMAX, 성남, 한국)를 사용하여 측정되 었다. 환자들을 높은 NKA (≥ 500 pg/mL) 그룹과 낮은 NKA (< 500 pg/mL) 그룹으로 나누어 종양의 진행, 신체 활동도, 전체 생존율 (OS), 무사건 생존율 (EFS)을 비교하였다.
결과: 높은 NKA 그룹은 낮은 NKA 그룹보다 유의하게 긴 OS (p < 0.01)와 EFS (p < 0.01)를 나타냈다. 종양 초기 단계 또는 높은 신체 활동도를 가진 환자들은 종양 진행 단계 또는 신체 활동도가 낮은 환 자들보다 더 높은 NKA 수치를 나타냈다.
결론: NKA는 위암 환자의 예후 인자로 활용할 수 있으며 향후 추가적인 연구가 필요할 것으로 사료된다.
목록